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Image-Guided Stereotactic Biopsy

  • Mar 13
  • 2 min read

Updated: May 21

Advancements in medical imaging and minimally invasive techniques have significantly improved the accuracy of diagnosing brain and spinal conditions. One such technique is Image-Guided Stereotactic Biopsy, a precise and minimally invasive procedure used to obtain tissue samples from abnormal areas in the brain or spine. This method plays a crucial role in diagnosing conditions such as tumours, infections, and inflammatory diseases while minimising risks associated with traditional open surgery.


What is an Image-Guided Stereotactic Biopsy?

An image-guided stereotactic biopsy is a specialised diagnostic procedure that uses advanced imaging technologies such as Magnetic Resonance Imaging (MRI), Computed Tomography (CT), or Fluoroscopy to precisely guide a needle to the target tissue. This technique enables neurosurgeons and interventional radiologists to safely extract tissue samples from deep or delicate areas of the brain and spine.


This biopsy method is essential in diagnosing:

  • Brain tumours (malignant or benign)

  • Spinal lesions (tumours or infections affecting the vertebrae or spinal cord)

  • Inflammatory or infectious conditions (such as encephalitis or spinal infections)

  • Neurodegenerative diseases (when tissue analysis is required for confirmation)


Benefits of Image-Guided Stereotactic Biopsy

  • Minimally Invasive: Reduces the need for open surgery, resulting in faster recovery.

  • High Accuracy: Real-time imaging ensures precise targeting of the lesion.

  • Lower Risk: Decreased risk of complications such as infection, bleeding, or damage to surrounding structures.

  • Shorter Recovery Time: Most patients resume normal activities within a day or two.

  • Essential for Diagnosis: Provides definitive tissue analysis to confirm or rule out serious conditions.


When is Image-Guided Stereotactic Biopsy Recommended?

This procedure is advised when imaging studies reveal an abnormality in the brain or spine that requires further evaluation. Common indications include:

Brain Conditions

  • Primary Brain Tumours: Gliomas, meningiomas, and other abnormal growths.

  • Metastatic Brain Lesions: Cancer that has spread to the brain from another part of the body.

  • Inflammatory or Infectious Brain Disorders: Conditions such as encephalitis, abscesses, or demyelinating diseases.

Spinal Conditions

  • Spinal Tumours: Both benign and malignant growths affecting the spinal cord or vertebrae.

  • Osteomyelitis and Spinal Infections: Infections of the spine requiring precise diagnosis for targeted treatment.

  • Unexplained Neurological Symptoms: Progressive weakness, numbness, or chronic pain of unknown origin.


Diagnosis and Treatment Process

Diagnosis: A comprehensive approach is used to determine the need for biopsy and potential treatment options. Steps include:

  • Medical History and Physical Examination

  • Advanced Imaging Studies (MRI, CT, PET scans)

  • Functional Assessments (For conditions affecting nerves or blood vessels)

Treatment Options After Biopsy: Once a diagnosis is confirmed, a personalised treatment plan is developed, which may include:

  • Targeted Medications: Chemotherapy, immunotherapy, or antibiotics for infections.

  • Stereotactic Radiosurgery (SRS) or Fractionated Stereotactic Radiotherapy (FSRT) for tumour management.

  • Surgical Intervention: If the biopsy confirms a tumour requiring removal.


Conclusion

Image-guided stereotactic biopsy is a vital tool in diagnosing brain and spinal conditions with high accuracy while minimising risks. When combined with advanced treatment options like Stereotactic Radiosurgery (SRS) and Fractionated Stereotactic Radiotherapy (FSRT), patients can benefit from safe and minimally invasive approaches to managing complex neurological conditions. Schedule a consultation with us today to learn more.



Dr Prem Pillay reviewing MRI scans with a patient at Singapore Brain Spine Nerves Centre, Mount Elizabeth Medical Centre.

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